
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
Zusammenfassung
Six-month follow-up to the 2016 open-label feasibility study of psilocybin with psychological support in treatment-resistant depression. Depressive symptom reductions (e.g., QIDS, HDRS) observed acutely and at 3 months persisted in a substantial proportion of participants at 6 months, with some cases of partial or full relapse, highlighting both durability and limits of effect. No new serious adverse events emerged. Findings support further controlled trials and exploration of maintenance strategies (e.g., additional therapeutic integration or booster dosing).
Schlüsselwörter
psilocybintreatment-resistant depressionfollow-uplong-term outcomesclinical research
Klinische Forschung
