Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Carhart-Harris, R.L., Erritzoe, D., Williams, T., Stone, J.M., Reed, L.J., Colasanti, A., Tyacke, R.J., Leech, R., Malizia, A.L., Murphy, K., Hobden, P., Evans, J., Feilding, A., Wise, R.G., Nutt, D.J. (2012) Proceedings of the National Academy of Sciences , 109(6) , 2138-2143
Abstract
This landmark fMRI study revealed that psilocybin decreases activity in hub regions of the brain, including the medial prefrontal cortex and posterior cingulate cortex, challenging assumptions about how psychedelics produce their characteristic effects on consciousness.
Keywords
psilocybinfMRIneural correlatesdefault mode networkconsciousness
Neuroscience