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Scientific Research

Significance and Potential of Psychedelics in Science

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial

Davis, A.K., Barrett, F.S., May, D.G., Cosimano, M.P., Sepeda, N.D., Johnson, M.W., Finan, P.H., Griffiths, R.R. (2021) JAMA Psychiatry , 78(5) , 481-489

Abstract

This randomized clinical trial investigated psilocybin-assisted therapy for major depressive disorder. Results showed that 71% of participants demonstrated clinically significant response at 4-week follow-up, with 54% achieving remission, suggesting rapid and sustained antidepressant effects.

Keywords

psilocybindepressionmajor depressive disorderclinical trialpsychedelic therapy
Clinical Research
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